Human Gene Editing

Interest in the precision gene-editing tool CRISPR has mushroomed in the half-dozen years since the technology was demonstrated to have enormous potential. In this edition of Issues, several of the leading thinkers in the field comment on the current status of society’s ability to understand and manage this powerful tool.

Editor's Journal

  • Editor’s Journal

    The first scientific papers about breakthrough developments in the use of the gene-editing tool CRISPR appeared in late 2012 and early 2013. Researchers soon recognized that this relatively accurate and easy-to-use technology… Read More

From the Hill

  • From the Hill – Spring 2019

    With the end of the border wall brouhaha, Congress passed omnibus legislation that set funding levels for fiscal year 2019. As anticipated, the budget includes substantive increases for key science agencies including… Read More



Book Reviews

  • Sandy Isenstadt, "Electric Light: An Architectural History" (2018)

    The Medium of Modernity

    Artificial illumination occupies a paradoxical position in modern daily life. It is a ubiquitous technology, pervading almost every interior space and shaping nighttime environments. Yet despite (or perhaps because of) its omnipresence,… Read More
  • Shobita Parthasarathy, "Patent Politics: Life Forms, Markets, and the Public Interest in the United States and Europe" (2017)

    Rights to Life?

    In 1996, the United States Patent and Trademark Office (PTO) awarded patent protection to Myriad Genetics for a gene that it had sequenced, called BRCA1, and a test for diagnosing mutations in… Read More
  • Kevin Werbach, "Blockchain and the New Architecture of Trust" (2018)

    Who Can You Trust?

    Kevin Werbach’s The Blockchain and the New Architecture of Trust offers easy-to-follow explanations of how a technology resting on foundations of mutual mistrust can become trustworthy. If you are interested in gaining… Read More
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