Monique Verdin, "Headwaters : Tamaracks + Time : Lake Itasca" (2019), digital assemblage. Photograph taken in 2019; United States War Department map of the route passed over by an expedition into the Indian country in 1832 to the source of the Mississippi River.

Human Gene Editing

Recent technological breakthroughs—most notably the development of CRISPR precision gene editing—have given scientists unprecedented power to manipulate the building blocks of life, including the human genome. Issues provides a critical platform for debating the ethics, regulation, risks, and benefits of this revolution in gene editing.