Working Proofs for State-Level Science
The past year’s cuts to science funding, haphazard layoffs and rehires at federal agencies, and myriad threats to federal support for research universities have left many researchers demoralized. In fast-moving and deeply uncomfortable times like this, the science community searches for a story about where we are going. After nearly 80 years of federally driven science policy, the stories in this issue demonstrate that states can be places where transformative ideas about the relationship between science and the public can emerge, possibly offering new models to connect the research enterprise with society’s needs.
Editor's Journal
The “Terrible Engine of Destruction” That Inspired Federal Science Funding
Read MoreThe story of how the federal government came to fund science to solve the problem of plagues of locusts in the 1870s offers insights into the relationship between science and the American public.

Gallery
Butter Cows and Seed Art and Participatory Spectacles
Perspectives
Simplify Research Regulations
Read MoreThe current policy environment offers a unique opportunity to act swiftly on the longstanding issue of burdensome research regulations.
Water Breathing Is a Blind Spot in Animal Welfare Science
Read MoreConsidering how water breathers differ from air breathers in policy and practice could improve welfare for these animals, both captive and wild.

Interview
“There Are Two Possible Futures for American Science.”
Poetry
Industry
Coming Soon

Gallery
A Capacity for World-Building
Real Numbers
Connecting the Dots for Defense STEM Workforce Development
Coming Soon
Features
How I Learned to Conduct Research That Makes a Difference in the Lives of Arizona’s Kids
Read MoreGabriel Shaibi was trained to gather evidence about diabetes prevention. To have an impact, he learned to gather partners.
A Texas-Sized, Texas-Shaped Approach to Biomedical Research
Read MoreSince 2007, Texas voters have approved $9 billion to chase cures for cancer and now dementia, embracing the idea that biomedical research is a force for public good, rather than a special interest handout to well-connected universities.
Research That Solves North Carolina’s Problems
Read MoreThe North Carolina Collaboratory is “working proof” of how state-directed research at universities can make publicly funded science accountable to the people of the state.
Fully Accounting for America’s Research Investments
Read MoreFar from being passive recipients of federal research dollars, universities pour in substantial resources of their own. It’s time to do a better job of documenting those investments.
Can Industrial Policy Still Do Big Things?
Read MoreA year after he left office, President Biden’s industrial policy is widely considered a failure. But the tools his administration developed are still in play and have defied a long-standing consensus about what is possible.
Who Will Build It?
Coming Soon
Repurposing Grand Challenges in Tumultuous Times
Coming Soon
Building Bridges—Not Walls—for Technological Sovereignty
Coming Soon
Why the Cloud Needs Competition
Coming Soon
Book Reviews

Making the Invisible Visible
Read MoreDrawing on nearly a decade of research, Diane M. Tober situates egg donors at the center of a sprawling, ethically thorny, and economically complex system. The result is one of the most detailed portraits yet of the hidden labor sustaining assisted reproduction.