Chesley Bonestell, “The Exploration of Mars” (1953), oil on board, 143/8 x 28 inches, gift of William Estler, Smithsonian National Air and Space Museum. Reproduced courtesy of Bonestell LLC.

Articles in Focus

Human Gene Editing

Recent technological breakthroughs—most notably the development of CRISPR precision gene editing—have given scientists unprecedented power to manipulate the building blocks of life, including the human genome. Issues provides a critical platform for debating the ethics, regulation, risks, and benefits of this revolution in gene editing.